The immune landscape of neuroblastoma: Challenges and opportunities for novel therapeutic strategies in pediatric oncology

Immunotherapy and Novel Combinations in Oncology: Current Landscape, Challenges, and Opportunities

Cancer treatments have been transformed with recent advances in cancer immunotherapy.1 As monotherapies, these agents have demonstrated clinical activity across many tumor types. Further advances in the effectiveness of cancer immunotherapies will require targeting antitumor immune response at multiple levels, which may be accomplished through combination approaches. This review discusses the c...

The International Congress of Challenges in Pediatric Hematology and Oncology (CPHO)

wuthering heights and the concept of marality/a sociological study of the novel

to discuss my point, i have collected quite a number of articles, anthologies, and books about "wuthering heights" applying various ideas and theories to this fantastic story. hence, i have come to believe that gadamer and jauss are rightful when they claim that "the individaul human mind is the center and origin of all meaning," 3 that reading literature is a reader-oriented activity, that it ...

efl students gender and socioeconomic status: the use of politeness strategies in the first and second languages

within the components of communicative competence, a special emphasis is put on the “rules of politeness,” specifically the politeness strategies (brown and levinson, 1978) that speakers deploy when performing the request speech act. this is because the degree of imposition that making a request places upon one’s interlocutor(s) has been seen to be influenced by several factors among which, as ...

Challenges and opportunities for oncology biomarker discovery.

Recent success of companion diagnostics along with the increasing regulatory pressure for better identification of the target population has created an unprecedented incentive for drug discovery companies to invest in novel strategies for biomarker discovery. In parallel with the rapid advancement and clinical adoption of high-throughput technologies, a number of knowledge management and system...